P271-0249 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-1,4-diazepane

P271-0249 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-1,4-diazepane
P271-0249 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-1,4-diazepane alternative view

Chemical Structure Depiction of ChemDiv screening compound P271-0249
1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-1,4-diazepane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P271-0249

Molecular Formula

C21H30N6O (C21 H30 N6 O)

Compound Name

1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-1,4-diazepane

IUPAC name

1-(1-{23-dimethylpyrido[23-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-methyl-14-diazepane

SMILES

Cc1c(C)nc2ncc(N(CCC3)CC3C(N3CCN(C)CCC3)=O)cc2n1

InChI

InChI=1S/C21H30N6O/c1-15-16(2)24-20-19(23-15)12-18(13-22-20)27-8-4-6-17(14-27)21(28)26-9-5-7-25(3)10-11-26/h12-13,17H,4-11,14H2,1-3H3/t17-/m0/s1

InChI Key

ZHAZMSYTRJEZON-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27570850

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.357

Distribution Coefficient, logD

-0.097

Water Solubility, LogSw

-1.74

Polar Surface Area

52.631

Acid Dissociation Constant (pKa)

22.59

Base Dissociation Constant (pKb)

8.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.90

P271-0249 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P271-0249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P271-0249?
Check Price and Availability of P271-0249, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P271-0249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P271-0249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P271-0249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P271-0249 available by request