P271-0375 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

P271-0375 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine
P271-0375 Screening compound: 1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P271-0375
1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P271-0375

Molecular Formula

C24H29N7O (C24 H29 N7 O)

Compound Name

1-(1-{2,3-dimethylpyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

IUPAC name

1-(1-{23-dimethylpyrido[23-b]pyrazin-7-yl}piperidine-3-carbonyl)-4-(pyridin-2-yl)piperazine

SMILES

Cc1c(C)nc2ncc(N(CCC3)CC3C(N(CC3)CCN3c3ncccc3)=O)cc2n1

InChI

InChI=1S/C24H29N7O/c1-17-18(2)28-23-21(27-17)14-20(15-26-23)31-9-5-6-19(16-31)24(32)30-12-10-29(11-13-30)22-7-3-4-8-25-22/h3-4,7-8,14-15,19H,5-6,9-13,16H2,1-2H3/t19-/m0/s1

InChI Key

VFUJFASUOVNJMA-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27570875

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.628

Distribution Coefficient, logD

2.619

Water Solubility, LogSw

-2.68

Polar Surface Area

60.595

Acid Dissociation Constant (pKa)

22.59

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.80

P271-0375 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Autophagy-Targeted Library (4564 compounds)

C-Met Library (15277 compounds)

KRAS-Targeted Library (16000 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P271-0375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P271-0375?
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What is the minimum amount of P271-0375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P271-0375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P271-0375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P271-0375 available by request