P271-0521 Screening compound: 1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide

P271-0521 Screening compound: 1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide
P271-0521 Screening compound: 1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P271-0521
1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P271-0521

Molecular Formula

C24H30N6O (C24 H30 N6 O)

Compound Name

1-{2,3-diethylpyrido[2,3-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide

IUPAC name

1-{23-diethylpyrido[23-b]pyrazin-7-yl}-N-[1-(pyridin-3-yl)ethyl]piperidine-3-carboxamide

SMILES

CCc1c(CC)nc2ncc(N(CCC3)CC3C(NC(C)c3cnccc3)=O)cc2n1

InChI

InChI=1S/C24H30N6O/c1-4-20-21(5-2)29-23-22(28-20)12-19(14-26-23)30-11-7-9-18(15-30)24(31)27-16(3)17-8-6-10-25-13-17/h6,8,10,12-14,16,18H,4-5,7,9,11,15H2,1-3H3,(H,27,31)

InChI Key

CJBLPZRYJNAECY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570911

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.708

Distribution Coefficient, logD

2.705

Water Solubility, LogSw

-2.76

Polar Surface Area

66.647

Acid Dissociation Constant (pKa)

12.99

Base Dissociation Constant (pKb)

5.14

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

45.80

P271-0521 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P271-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P271-0521?
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What is the minimum amount of P271-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P271-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P271-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P271-0521 available by request