P273-0728 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide

P273-0728 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide
P273-0728 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P273-0728
1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P273-0728

Molecular Formula

C25H29N5O3 (C25 H29 N5 O3)

Compound Name

1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide

IUPAC name

1-[3-(5-cyclobutyl-124-oxadiazol-3-yl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]piperidine-3-carboxamide

SMILES

COc1ccc(CNC(C(CCC2)CN2c2ncccc2-c2noc(C3CCC3)n2)=O)cc1

InChI

InChI=1S/C25H29N5O3/c1-32-20-11-9-17(10-12-20)15-27-24(31)19-7-4-14-30(16-19)23-21(8-3-13-26-23)22-28-25(33-29-22)18-5-2-6-18/h3,8-13,18-19H,2,4-7,14-16H2,1H3,(H,27,31)/t19-/m0/s1

InChI Key

MURYKOUTZNICKA-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27571205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.469

Distribution Coefficient, logD

2.338

Water Solubility, LogSw

-3.60

Polar Surface Area

76.491

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

8.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

P273-0728 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P273-0728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P273-0728?
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What is the minimum amount of P273-0728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P273-0728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P273-0728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P273-0728 available by request