P273-0731 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide

P273-0731 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide
P273-0731 Screening compound: 1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P273-0731
1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P273-0731

Molecular Formula

C25H29N5O2 (C25 H29 N5 O2)

Compound Name

1-[3-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide

IUPAC name

1-[3-(5-cyclobutyl-124-oxadiazol-3-yl)pyridin-2-yl]-N-[(2-methylphenyl)methyl]piperidine-3-carboxamide

SMILES

Cc1c(CNC(C(CCC2)CN2c2ncccc2-c2noc(C3CCC3)n2)=O)cccc1

InChI

InChI=1S/C25H29N5O2/c1-17-7-2-3-8-19(17)15-27-24(31)20-11-6-14-30(16-20)23-21(12-5-13-26-23)22-28-25(32-29-22)18-9-4-10-18/h2-3,5,7-8,12-13,18,20H,4,6,9-11,14-16H2,1H3,(H,27,31)/t20-/m0/s1

InChI Key

DDLHLEHVVDYIFQ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27571207

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.375

Distribution Coefficient, logD

3.244

Water Solubility, LogSw

-4.21

Polar Surface Area

68.947

Acid Dissociation Constant (pKa)

11.65

Base Dissociation Constant (pKb)

8.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

P273-0731 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P273-0731 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P273-0731?
Check Price and Availability of P273-0731, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P273-0731 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P273-0731
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P273-0731
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P273-0731 available by request