P277-0105 Screening compound: 5-chloro-N-{[1,2,4]triazolo[4,3-a]pyridin-8-yl}thiophene-2-carboxamide

P277-0105 Screening compound: 5-chloro-N-{[1,2,4]triazolo[4,3-a]pyridin-8-yl}thiophene-2-carboxamide
P277-0105 Screening compound: 5-chloro-N-{[1,2,4]triazolo[4,3-a]pyridin-8-yl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P277-0105
5-chloro-N-{[1,2,4]triazolo[4,3-a]pyridin-8-yl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P277-0105

Molecular Formula

C11H7ClN4OS (C11 H7 ClN4 OS)

Compound Name

5-chloro-N-{[1,2,4]triazolo[4,3-a]pyridin-8-yl}thiophene-2-carboxamide

IUPAC name

5-chloro-N-{[124]triazolo[43-a]pyridin-8-yl}thiophene-2-carboxamide

SMILES

O=C(c(s1)ccc1Cl)Nc1cccn2c1nnc2

InChI

InChI=1S/C11H7ClN4OS/c12-9-4-3-8(18-9)11(17)14-7-2-1-5-16-6-13-15-10(7)16/h1-6H,(H,14,17)

InChI Key

YWDXGIXVWLYAEP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27571248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

278.72

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.014

Distribution Coefficient, logD

2.001

Water Solubility, LogSw

-2.78

Polar Surface Area

47.249

Acid Dissociation Constant (pKa)

8.92

Base Dissociation Constant (pKb)

1.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

P277-0105 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P277-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P277-0105?
Check Price and Availability of P277-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P277-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P277-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P277-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P277-0105 available by request