P277-1112 Screening compound: N~4~-(3-cyclobutyl[1,2,4]triazolo[4,3-a]pyridin-8-yl)isonicotinamide

P277-1112 Screening compound: N~4~-(3-cyclobutyl[1,2,4]triazolo[4,3-a]pyridin-8-yl)isonicotinamide
P277-1112 Screening compound: N~4~-(3-cyclobutyl[1,2,4]triazolo[4,3-a]pyridin-8-yl)isonicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P277-1112
N~4~-(3-cyclobutyl[1,2,4]triazolo[4,3-a]pyridin-8-yl)isonicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P277-1112

Molecular Formula

C16H15N5O (C16 H15 N5 O)

Compound Name

N~4~-(3-cyclobutyl[1,2,4]triazolo[4,3-a]pyridin-8-yl)isonicotinamide

IUPAC name

N-{3-cyclobutyl-[124]triazolo[43-a]pyridin-8-yl}pyridine-4-carboxamide

SMILES

O=C(c1ccncc1)Nc1cccn2c1nnc2C1CCC1

InChI

InChI=1S/C16H15N5O/c22-16(12-6-8-17-9-7-12)18-13-5-2-10-21-14(11-3-1-4-11)19-20-15(13)21/h2,5-11H,1,3-4H2,(H,18,22)

InChI Key

VRNMICUDMCAMCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27571336

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

293.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.807

Distribution Coefficient, logD

0.801

Water Solubility, LogSw

-1.04

Polar Surface Area

54.468

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

2.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

P277-1112 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P277-1112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P277-1112?
Check Price and Availability of P277-1112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P277-1112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P277-1112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P277-1112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P277-1112 available by request