P294-1831 Screening compound: 3-({2-cyclopropyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-1-(3,4-difluorobenzenesulfonyl)piperidine

P294-1831 Screening compound: 3-({2-cyclopropyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-1-(3,4-difluorobenzenesulfonyl)piperidine
P294-1831 Screening compound: 3-({2-cyclopropyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-1-(3,4-difluorobenzenesulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P294-1831
3-({2-cyclopropyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-1-(3,4-difluorobenzenesulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P294-1831

Molecular Formula

C21H22F2N4O2S (C21 H22 F2 N4 O2 S)

Compound Name

3-({2-cyclopropyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-1-(3,4-difluorobenzenesulfonyl)piperidine

IUPAC name

3-({2-cyclopropyl-3H-imidazo[45-b]pyridin-3-yl}methyl)-1-(34-difluorobenzenesulfonyl)piperidine

SMILES

O=S(c(cc1)cc(F)c1F)(N1CC(Cn2c3ncccc3nc2C2CC2)CCC1)=O

InChI

InChI=1S/C21H22F2N4O2S/c22-17-8-7-16(11-18(17)23)30(28,29)26-10-2-3-14(12-26)13-27-20(15-5-6-15)25-19-4-1-9-24-21(19)27/h1,4,7-9,11,14-15H,2-3,5-6,10,12-13H2/t14-/m0/s1

InChI Key

SYDFASMLHVBFPD-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD29004159

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.048

Distribution Coefficient, logD

4.048

Water Solubility, LogSw

-4.26

Polar Surface Area

51.970

Acid Dissociation Constant (pKa)

22.32

Base Dissociation Constant (pKb)

4.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

P294-1831 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P294-1831 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P294-1831?
Check Price and Availability of P294-1831, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P294-1831 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P294-1831
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P294-1831
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P294-1831 available by request