P294-1977 Screening compound: 1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

P294-1977 Screening compound: 1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine
P294-1977 Screening compound: 1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P294-1977
1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P294-1977

Molecular Formula

C19H21FN4O2S (C19 H21 FN4 O2 S)

Compound Name

1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

IUPAC name

1-(4-fluoro-3-methylbenzenesulfonyl)-3-({3H-imidazo[45-b]pyridin-3-yl}methyl)piperidine

SMILES

Cc(cc(cc1)S(N2CC(Cn3c4ncccc4nc3)CCC2)(=O)=O)c1F

InChI

InChI=1S/C19H21FN4O2S/c1-14-10-16(6-7-17(14)20)27(25,26)24-9-3-4-15(12-24)11-23-13-22-18-5-2-8-21-19(18)23/h2,5-8,10,13,15H,3-4,9,11-12H2,1H3/t15-/m1/s1

InChI Key

KILAKRHEPRCQHG-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD29004287

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.616

Distribution Coefficient, logD

2.616

Water Solubility, LogSw

-2.73

Polar Surface Area

51.974

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

2.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.80

P294-1977 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P294-1977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P294-1977?
Check Price and Availability of P294-1977, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P294-1977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P294-1977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P294-1977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P294-1977 available by request