P294-2020 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

P294-2020 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine
P294-2020 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P294-2020
1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P294-2020

Molecular Formula

C19H21ClN4O3S (C19 H21 ClN4 O3 S)

Compound Name

1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[4,5-b]pyridin-3-yl}methyl)piperidine

IUPAC name

1-(5-chloro-2-methoxybenzenesulfonyl)-3-({3H-imidazo[45-b]pyridin-3-yl}methyl)piperidine

SMILES

COc(ccc(Cl)c1)c1S(N1CC(Cn2c3ncccc3nc2)CCC1)(=O)=O

InChI

InChI=1S/C19H21ClN4O3S/c1-27-17-7-6-15(20)10-18(17)28(25,26)24-9-3-4-14(12-24)11-23-13-22-16-5-2-8-21-19(16)23/h2,5-8,10,13-14H,3-4,9,11-12H2,1H3/t14-/m1/s1

InChI Key

BBEKLOBPZXGYLO-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29004083

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.401

Distribution Coefficient, logD

2.401

Water Solubility, LogSw

-2.87

Polar Surface Area

59.605

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

2.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.80

P294-2020 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antifungal Library (16415 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GABA Library (7115 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Hemic and lymphatic
  • Eye
  • Cancer
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Targets:
  • GPCR
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P294-2020 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P294-2020?
Check Price and Availability of P294-2020, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P294-2020 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P294-2020
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P294-2020
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P294-2020 available by request