P294-2217 Screening compound: 3-({2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide

P294-2217 Screening compound: 3-({2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide
P294-2217 Screening compound: 3-({2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P294-2217
3-({2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P294-2217

Molecular Formula

C21H22F3N5O (C21 H22 F3 N5 O)

Compound Name

3-({2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide

IUPAC name

3-({2-methyl-3H-imidazo[45-b]pyridin-3-yl}methyl)-N-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide

SMILES

Cc1nc2cccnc2n1CC(CCC1)CN1C(Nc1ccc(C(F)(F)F)cc1)=O

InChI

InChI=1S/C21H22F3N5O/c1-14-26-18-5-2-10-25-19(18)29(14)13-15-4-3-11-28(12-15)20(30)27-17-8-6-16(7-9-17)21(22,23)24/h2,5-10,15H,3-4,11-13H2,1H3,(H,27,30)/t15-/m0/s1

InChI Key

JUMZAQABSHGYDF-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29004149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.867

Distribution Coefficient, logD

3.867

Water Solubility, LogSw

-3.99

Polar Surface Area

46.253

Acid Dissociation Constant (pKa)

13.90

Base Dissociation Constant (pKb)

3.38

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

P294-2217 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P294-2217 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P294-2217?
Check Price and Availability of P294-2217, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P294-2217 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P294-2217
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P294-2217
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P294-2217 available by request