P297-4526 Screening compound: N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

P297-4526 Screening compound: N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide
P297-4526 Screening compound: N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P297-4526
N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P297-4526

Molecular Formula

C23H27N5O2 (C23 H27 N5 O2)

Compound Name

N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

IUPAC name

N-cyclopentyl-3-[2-(4-methoxyphenyl)-3H-imidazo[45-b]pyridin-3-yl]pyrrolidine-1-carboxamide

SMILES

COc(cc1)ccc1-c1nc2cccnc2n1C(CC1)CN1C(NC1CCCC1)=O

InChI

InChI=1S/C23H27N5O2/c1-30-19-10-8-16(9-11-19)21-26-20-7-4-13-24-22(20)28(21)18-12-14-27(15-18)23(29)25-17-5-2-3-6-17/h4,7-11,13,17-18H,2-3,5-6,12,14-15H2,1H3,(H,25,29)/t18-/m1/s1

InChI Key

JFOLLEDVPLSXFN-GOSISDBHSA-N

MDL Number (MFCD)

MFCD29023921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.907

Distribution Coefficient, logD

3.907

Water Solubility, LogSw

-3.96

Polar Surface Area

54.912

Acid Dissociation Constant (pKa)

17.27

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

P297-4526 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P297-4526 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P297-4526?
Check Price and Availability of P297-4526, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P297-4526 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P297-4526
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P297-4526
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P297-4526 available by request