P297-4725 Screening compound: 3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine

P297-4725 Screening compound: 3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine
P297-4725 Screening compound: 3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P297-4725
3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P297-4725

Molecular Formula

C24H24N4O3S (C24 H24 N4 O3 S)

Compound Name

3-[2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine

IUPAC name

3-[2-(4-methoxyphenyl)-3H-imidazo[45-b]pyridin-3-yl]-1-phenylmethanesulfonylpyrrolidine

SMILES

COc(cc1)ccc1-c1nc2cccnc2n1C(CC1)CN1S(Cc1ccccc1)(=O)=O

InChI

InChI=1S/C24H24N4O3S/c1-31-21-11-9-19(10-12-21)23-26-22-8-5-14-25-24(22)28(23)20-13-15-27(16-20)32(29,30)17-18-6-3-2-4-7-18/h2-12,14,20H,13,15-17H2,1H3

InChI Key

PXJOXZVPJZDJBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024023

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.497

Distribution Coefficient, logD

3.497

Water Solubility, LogSw

-3.62

Polar Surface Area

59.635

Acid Dissociation Constant (pKa)

17.36

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

P297-4725 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P297-4725 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P297-4725?
Check Price and Availability of P297-4725, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P297-4725 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P297-4725
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P297-4725
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P297-4725 available by request