P297-4749 Screening compound: 1-(2,3-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine

P297-4749 Screening compound: 1-(2,3-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine
P297-4749 Screening compound: 1-(2,3-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P297-4749
1-(2,3-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P297-4749

Molecular Formula

C23H22N4O3S (C23 H22 N4 O3 S)

Compound Name

1-(2,3-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine

IUPAC name

1-(23-dihydro-1H-indene-5-sulfonyl)-3-[2-(furan-3-yl)-3H-imidazo[45-b]pyridin-3-yl]pyrrolidine

SMILES

O=S(c1cc(CCC2)c2cc1)(N(CC1)CC1n1c2ncccc2nc1-c1cocc1)=O

InChI

InChI=1S/C23H22N4O3S/c28-31(29,20-7-6-16-3-1-4-17(16)13-20)26-11-8-19(14-26)27-22(18-9-12-30-15-18)25-21-5-2-10-24-23(21)27/h2,5-7,9-10,12-13,15,19H,1,3-4,8,11,14H2/t19-/m1/s1

InChI Key

LHWSCVOGRUPSFI-LJQANCHMSA-N

MDL Number (MFCD)

MFCD29024033

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.892

Distribution Coefficient, logD

3.892

Water Solubility, LogSw

-4.02

Polar Surface Area

60.287

Acid Dissociation Constant (pKa)

16.99

Base Dissociation Constant (pKb)

2.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

P297-4749 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P297-4749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P297-4749?
Check Price and Availability of P297-4749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P297-4749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P297-4749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P297-4749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P297-4749 available by request