P300-2149 Screening compound: 5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

P300-2149 Screening compound: 5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide
P300-2149 Screening compound: 5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P300-2149
5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P300-2149

Molecular Formula

C25H20FN5O2 (C25 H20 FN5 O2)

Compound Name

5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

IUPAC name

5-[(4-fluorophenyl)methyl]-4-oxo-N-[2-(pyridin-3-yl)ethyl]-4H5H-pyrazolo[15-a]quinoxaline-7-carboxamide

SMILES

O=C(c(cc1)cc(N2Cc(cc3)ccc3F)c1-n1nccc1C2=O)NCCc1cnccc1

InChI

InChI=1S/C25H20FN5O2/c26-20-6-3-18(4-7-20)16-30-23-14-19(24(32)28-12-9-17-2-1-11-27-15-17)5-8-21(23)31-22(25(30)33)10-13-29-31/h1-8,10-11,13-15H,9,12,16H2,(H,28,32)

InChI Key

SDAQVGPFBBDYQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28993236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.067

Distribution Coefficient, logD

2.065

Water Solubility, LogSw

-2.46

Polar Surface Area

61.612

Acid Dissociation Constant (pKa)

13.68

Base Dissociation Constant (pKb)

4.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

P300-2149 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with P300-2149 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P300-2149?
Check Price and Availability of P300-2149, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P300-2149 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P300-2149
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P300-2149
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P300-2149 available by request