P307-0712 Screening compound: 8-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

P307-0712 Screening compound: 8-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
P307-0712 Screening compound: 8-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P307-0712
8-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P307-0712

Molecular Formula

C14H15ClN4O3 (C14 H15 ClN4 O3)

Compound Name

8-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{6-chloroimidazo[12-b]pyridazine-2-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c(nc1cc2)cn1nc2Cl)N(CC1)CCC11OCCO1

InChI

InChI=1S/C14H15ClN4O3/c15-11-1-2-12-16-10(9-19(12)17-11)13(20)18-5-3-14(4-6-18)21-7-8-22-14/h1-2,9H,3-8H2

InChI Key

MGLIDBOLSMODSF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.75

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.577

Distribution Coefficient, logD

0.577

Water Solubility, LogSw

-1.94

Polar Surface Area

50.886

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

1.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

P307-0712 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P307-0712 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P307-0712?
Check Price and Availability of P307-0712, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P307-0712 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P307-0712
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P307-0712
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P307-0712 available by request