P307-0721 Screening compound: 1-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-4-(2,3-dimethylphenyl)piperazine

P307-0721 Screening compound: 1-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-4-(2,3-dimethylphenyl)piperazine
P307-0721 Screening compound: 1-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-4-(2,3-dimethylphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P307-0721
1-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-4-(2,3-dimethylphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P307-0721

Molecular Formula

C19H20ClN5O (C19 H20 ClN5 O)

Compound Name

1-{6-chloroimidazo[1,2-b]pyridazine-2-carbonyl}-4-(2,3-dimethylphenyl)piperazine

IUPAC name

1-{6-chloroimidazo[12-b]pyridazine-2-carbonyl}-4-(23-dimethylphenyl)piperazine

SMILES

Cc1cccc(N(CC2)CCN2C(c(nc2cc3)cn2nc3Cl)=O)c1C

InChI

InChI=1S/C19H20ClN5O/c1-13-4-3-5-16(14(13)2)23-8-10-24(11-9-23)19(26)15-12-25-18(21-15)7-6-17(20)22-25/h3-7,12H,8-11H2,1-2H3

InChI Key

WDOJCUPSNUJIDS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021559

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.85

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.274

Distribution Coefficient, logD

3.273

Water Solubility, LogSw

-3.40

Polar Surface Area

39.409

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

P307-0721 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P307-0721 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P307-0721?
Check Price and Availability of P307-0721, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P307-0721 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P307-0721
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P307-0721
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P307-0721 available by request