P309-1164 Screening compound: N-{3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide

P309-1164 Screening compound: N-{3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide
P309-1164 Screening compound: N-{3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P309-1164
N-{3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P309-1164

Molecular Formula

C25H27N5O2 (C25 H27 N5 O2)

Compound Name

N-{3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide

IUPAC name

N-{3-[4-(23-dimethylphenyl)piperazine-1-carbonyl]pyrazin-2-yl}-4-methylbenzamide

SMILES

Cc(cc1)ccc1C(Nc1nccnc1C(N(CC1)CCN1c1c(C)c(C)ccc1)=O)=O

InChI

InChI=1S/C25H27N5O2/c1-17-7-9-20(10-8-17)24(31)28-23-22(26-11-12-27-23)25(32)30-15-13-29(14-16-30)21-6-4-5-18(2)19(21)3/h4-12H,13-16H2,1-3H3,(H,27,28,31)

InChI Key

IJKZPLMCBWEMAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27571419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.982

Distribution Coefficient, logD

2.448

Water Solubility, LogSw

-3.99

Polar Surface Area

62.443

Acid Dissociation Constant (pKa)

5.88

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

P309-1164 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P309-1164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P309-1164?
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What is the minimum amount of P309-1164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P309-1164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P309-1164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P309-1164 available by request