P316-0272 Screening compound: (2-chloro-6-fluorophenyl)-N-[1-(4-methoxyphenyl)-2-oxotetrahydro-1H-pyrrol-3-yl]methanesulfonamide

P316-0272 Screening compound: (2-chloro-6-fluorophenyl)-N-[1-(4-methoxyphenyl)-2-oxotetrahydro-1H-pyrrol-3-yl]methanesulfonamide
P316-0272 Screening compound: (2-chloro-6-fluorophenyl)-N-[1-(4-methoxyphenyl)-2-oxotetrahydro-1H-pyrrol-3-yl]methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P316-0272
(2-chloro-6-fluorophenyl)-N-[1-(4-methoxyphenyl)-2-oxotetrahydro-1H-pyrrol-3-yl]methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P316-0272

Molecular Formula

C18H18ClFN2O4S (C18 H18 ClFN2 O4 S)

Compound Name

(2-chloro-6-fluorophenyl)-N-[1-(4-methoxyphenyl)-2-oxotetrahydro-1H-pyrrol-3-yl]methanesulfonamide

IUPAC name

n/a

SMILES

COc(cc1)ccc1N(CCC1NS(Cc(c(F)ccc2)c2Cl)(=O)=O)C1=O

InChI

InChI=1S/C18H18ClFN2O4S/c1-26-13-7-5-12(6-8-13)22-10-9-17(18(22)23)21-27(24,25)11-14-15(19)3-2-4-16(14)20/h2-8,17,21H,9-11H2,1H3/t17-/m0/s1

InChI Key

BMPALBMSCZKVEV-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27572355

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.87

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.945

Distribution Coefficient, logD

2.945

Water Solubility, LogSw

-3.56

Polar Surface Area

67.843

Acid Dissociation Constant (pKa)

11.38

Base Dissociation Constant (pKb)

-2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

P316-0272 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with P316-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P316-0272?
Check Price and Availability of P316-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P316-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P316-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P316-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P316-0272 available by request