P321-0026 Screening compound: N-[(2,5-difluorophenyl)methyl]-1-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxamide

P321-0026 Screening compound: N-[(2,5-difluorophenyl)methyl]-1-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxamide
P321-0026 Screening compound: N-[(2,5-difluorophenyl)methyl]-1-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P321-0026
N-[(2,5-difluorophenyl)methyl]-1-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P321-0026

Molecular Formula

C21H20F2N4O2 (C21 H20 F2 N4 O2)

Compound Name

N-[(2,5-difluorophenyl)methyl]-1-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxamide

IUPAC name

N-[(25-difluorophenyl)methyl]-1-(5-phenyl-134-oxadiazol-2-yl)piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1nnc(-c2ccccc2)o1)NCc(cc(cc1)F)c1F

InChI

InChI=1S/C21H20F2N4O2/c22-17-6-7-18(23)16(12-17)13-24-19(28)14-8-10-27(11-9-14)21-26-25-20(29-21)15-4-2-1-3-5-15/h1-7,12,14H,8-11,13H2,(H,24,28)

InChI Key

PAVKXBCIQWWDBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27572520

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.160

Distribution Coefficient, logD

3.160

Water Solubility, LogSw

-3.27

Polar Surface Area

58.691

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

P321-0026 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P321-0026 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P321-0026?
Check Price and Availability of P321-0026, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P321-0026 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P321-0026
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P321-0026
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P321-0026 available by request