P327-0224 Screening compound: 2,5-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

P327-0224 Screening compound: 2,5-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide
P327-0224 Screening compound: 2,5-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-0224
2,5-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-0224

Molecular Formula

C18H18N2O2S2 (C18 H18 N2 O2 S2)

Compound Name

2,5-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

IUPAC name

25-dimethyl-N-{[4-(methylsulfanyl)phenyl]methyl}-4-oxo-4H5H-thieno[32-c]pyridine-3-carboxamide

SMILES

Cc1c(C(NCc(cc2)ccc2SC)=O)c(C(N(C)C=C2)=O)c2s1

InChI

InChI=1S/C18H18N2O2S2/c1-11-15(16-14(24-11)8-9-20(2)18(16)22)17(21)19-10-12-4-6-13(23-3)7-5-12/h4-9H,10H2,1-3H3,(H,19,21)

InChI Key

DBRKENYWFQXXIW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29020957

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.608

Distribution Coefficient, logD

2.608

Water Solubility, LogSw

-2.94

Polar Surface Area

41.100

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

-6.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

P327-0224 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with P327-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-0224?
Check Price and Availability of P327-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P327-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-0224 available by request