P327-1358 Screening compound: 5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

P327-1358 Screening compound: 5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide
P327-1358 Screening compound: 5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-1358
5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-1358

Molecular Formula

C24H21FN2O3S (C24 H21 FN2 O3 S)

Compound Name

5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

IUPAC name

5-[(4-fluorophenyl)methyl]-N-[(2-methoxyphenyl)methyl]-2-methyl-4-oxo-4H5H-thieno[32-c]pyridine-3-carboxamide

SMILES

Cc1c(C(NCc(cccc2)c2OC)=O)c(C(N(Cc(cc2)ccc2F)C=C2)=O)c2s1

InChI

InChI=1S/C24H21FN2O3S/c1-15-21(23(28)26-13-17-5-3-4-6-19(17)30-2)22-20(31-15)11-12-27(24(22)29)14-16-7-9-18(25)10-8-16/h3-12H,13-14H2,1-2H3,(H,26,28)

InChI Key

SWCAGLJHGMWYFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.846

Distribution Coefficient, logD

3.846

Water Solubility, LogSw

-4.23

Polar Surface Area

48.743

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

-6.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

P327-1358 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P327-1358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-1358?
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What is the minimum amount of P327-1358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-1358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-1358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-1358 available by request