P327-1370 Screening compound: 5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

P327-1370 Screening compound: 5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H,5H-thieno[3,2-c]pyridine-3-carboxamide
P327-1370 Screening compound: 5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H,5H-thieno[3,2-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-1370
5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-1370

Molecular Formula

C22H18FN3O2S (C22 H18 FN3 O2 S)

Compound Name

5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

IUPAC name

5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-N-[(pyridin-3-yl)methyl]-4H5H-thieno[32-c]pyridine-3-carboxamide

SMILES

Cc1c(C(NCc2cnccc2)=O)c(C(N(Cc(cc2)ccc2F)C=C2)=O)c2s1

InChI

InChI=1S/C22H18FN3O2S/c1-14-19(21(27)25-12-16-3-2-9-24-11-16)20-18(29-14)8-10-26(22(20)28)13-15-4-6-17(23)7-5-15/h2-11H,12-13H2,1H3,(H,25,27)

InChI Key

HYHDVMLQKGLUNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021072

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.397

Distribution Coefficient, logD

2.397

Water Solubility, LogSw

-2.25

Polar Surface Area

50.631

Acid Dissociation Constant (pKa)

12.19

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

P327-1370 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P327-1370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-1370?
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What is the minimum amount of P327-1370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-1370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-1370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-1370 available by request