P327-1444 Screening compound: N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

P327-1444 Screening compound: N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide
P327-1444 Screening compound: N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-1444
N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-1444

Molecular Formula

C19H17FN2O2S (C19 H17 FN2 O2 S)

Compound Name

N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

IUPAC name

N-cyclopropyl-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H5H-thieno[32-c]pyridine-3-carboxamide

SMILES

Cc1c(C(NC2CC2)=O)c(C(N(Cc(cc2)ccc2F)C=C2)=O)c2s1

InChI

InChI=1S/C19H17FN2O2S/c1-11-16(18(23)21-14-6-7-14)17-15(25-11)8-9-22(19(17)24)10-12-2-4-13(20)5-3-12/h2-5,8-9,14H,6-7,10H2,1H3,(H,21,23)

InChI Key

VZHGEOPLEZUTFO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.512

Distribution Coefficient, logD

2.512

Water Solubility, LogSw

-2.74

Polar Surface Area

41.169

Acid Dissociation Constant (pKa)

12.03

Base Dissociation Constant (pKb)

-5.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

P327-1444 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P327-1444 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-1444?
Check Price and Availability of P327-1444, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P327-1444 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-1444
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-1444
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-1444 available by request