P327-1453 Screening compound: N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

P327-1453 Screening compound: N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide
P327-1453 Screening compound: N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-1453
N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-1453

Molecular Formula

C20H19FN2O2S (C20 H19 FN2 O2 S)

Compound Name

N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-3-carboxamide

IUPAC name

N-(cyclopropylmethyl)-5-[(4-fluorophenyl)methyl]-2-methyl-4-oxo-4H5H-thieno[32-c]pyridine-3-carboxamide

SMILES

Cc1c(C(NCC2CC2)=O)c(C(N(Cc(cc2)ccc2F)C=C2)=O)c2s1

InChI

InChI=1S/C20H19FN2O2S/c1-12-17(19(24)22-10-13-2-3-13)18-16(26-12)8-9-23(20(18)25)11-14-4-6-15(21)7-5-14/h4-9,13H,2-3,10-11H2,1H3,(H,22,24)

InChI Key

XXNVOVWFEPLENN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021086

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.955

Distribution Coefficient, logD

2.955

Water Solubility, LogSw

-3.29

Polar Surface Area

41.636

Acid Dissociation Constant (pKa)

14.30

Base Dissociation Constant (pKb)

-2.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

P327-1453 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P327-1453 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-1453?
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What is the minimum amount of P327-1453 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-1453
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-1453
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-1453 available by request