P327-1778 Screening compound: 2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,5H-thieno[3,2-c]pyridin-4-one

P327-1778 Screening compound: 2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,5H-thieno[3,2-c]pyridin-4-one
P327-1778 Screening compound: 2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,5H-thieno[3,2-c]pyridin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P327-1778
2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,5H-thieno[3,2-c]pyridin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P327-1778

Molecular Formula

C22H26N4O2S (C22 H26 N4 O2 S)

Compound Name

2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,5H-thieno[3,2-c]pyridin-4-one

IUPAC name

2-methyl-5-(2-methylpropyl)-3-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H5H-thieno[32-c]pyridin-4-one

SMILES

CC(C)CN(C=Cc1c2c(C(N(CC3)CCN3c3ncccc3)=O)c(C)s1)C2=O

InChI

InChI=1S/C22H26N4O2S/c1-15(2)14-26-9-7-17-20(22(26)28)19(16(3)29-17)21(27)25-12-10-24(11-13-25)18-6-4-5-8-23-18/h4-9,15H,10-14H2,1-3H3

InChI Key

BUFIRWFYWUDQNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021118

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.402

Distribution Coefficient, logD

3.393

Water Solubility, LogSw

-3.71

Polar Surface Area

45.391

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

P327-1778 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P327-1778 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P327-1778?
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What is the minimum amount of P327-1778 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P327-1778
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P327-1778
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P327-1778 available by request