P349-0891 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[1,2-a]pyrazin-3-yl}amino)propan-1-one

P349-0891 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[1,2-a]pyrazin-3-yl}amino)propan-1-one
P349-0891 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[1,2-a]pyrazin-3-yl}amino)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P349-0891
1-{[1,4'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[1,2-a]pyrazin-3-yl}amino)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P349-0891

Molecular Formula

C25H32N6O (C25 H32 N6 O)

Compound Name

1-{[1,4'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[1,2-a]pyrazin-3-yl}amino)propan-1-one

IUPAC name

1-{[14'-bipiperidin]-1'-yl}-3-({2-phenylimidazo[12-a]pyrazin-3-yl}amino)propan-1-one

SMILES

O=C(CCNc1c(-c2ccccc2)nc2n1ccnc2)N(CC1)CCC1N1CCCCC1

InChI

InChI=1S/C25H32N6O/c32-23(30-16-10-21(11-17-30)29-14-5-2-6-15-29)9-12-27-25-24(20-7-3-1-4-8-20)28-22-19-26-13-18-31(22)25/h1,3-4,7-8,13,18-19,21,27H,2,5-6,9-12,14-17H2

InChI Key

DRLHZMNJIOZZEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573342

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.432

Distribution Coefficient, logD

-1.124

Water Solubility, LogSw

-2.34

Polar Surface Area

47.846

Acid Dissociation Constant (pKa)

20.43

Base Dissociation Constant (pKb)

10.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

P349-0891 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P349-0891 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P349-0891?
Check Price and Availability of P349-0891, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P349-0891 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P349-0891
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P349-0891
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P349-0891 available by request