P349-1177 Screening compound: 3-{[2-(4-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide

P349-1177 Screening compound: 3-{[2-(4-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide
P349-1177 Screening compound: 3-{[2-(4-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P349-1177
3-{[2-(4-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P349-1177

Molecular Formula

C20H25N5O (C20 H25 N5 O)

Compound Name

3-{[2-(4-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide

IUPAC name

3-{[2-(4-methylphenyl)imidazo[12-a]pyrazin-3-yl]amino}-N-(2-methylpropyl)propanamide

SMILES

CC(C)CNC(CCNc1c(-c2ccc(C)cc2)nc2n1ccnc2)=O

InChI

InChI=1S/C20H25N5O/c1-14(2)12-23-18(26)8-9-22-20-19(16-6-4-15(3)5-7-16)24-17-13-21-10-11-25(17)20/h4-7,10-11,13-14,22H,8-9,12H2,1-3H3,(H,23,26)

InChI Key

NUMUISWVYBDZHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573383

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.624

Distribution Coefficient, logD

2.623

Water Solubility, LogSw

-2.73

Polar Surface Area

53.103

Acid Dissociation Constant (pKa)

15.72

Base Dissociation Constant (pKb)

4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

P349-1177 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P349-1177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P349-1177?
Check Price and Availability of P349-1177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P349-1177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P349-1177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P349-1177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P349-1177 available by request