P349-2111 Screening compound: 3-{[2-(2-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide

P349-2111 Screening compound: 3-{[2-(2-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide
P349-2111 Screening compound: 3-{[2-(2-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P349-2111
3-{[2-(2-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P349-2111

Molecular Formula

C21H21N5OS (C21 H21 N5 OS)

Compound Name

3-{[2-(2-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide

IUPAC name

3-{[2-(2-methylphenyl)imidazo[12-a]pyrazin-3-yl]amino}-N-[(thiophen-2-yl)methyl]propanamide

SMILES

Cc(cccc1)c1-c1c(NCCC(NCc2cccs2)=O)n(ccnc2)c2n1

InChI

InChI=1S/C21H21N5OS/c1-15-5-2-3-7-17(15)20-21(26-11-10-22-14-18(26)25-20)23-9-8-19(27)24-13-16-6-4-12-28-16/h2-7,10-12,14,23H,8-9,13H2,1H3,(H,24,27)

InChI Key

DWOWCLUIMGJKHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.031

Distribution Coefficient, logD

3.031

Water Solubility, LogSw

-3.17

Polar Surface Area

53.850

Acid Dissociation Constant (pKa)

13.61

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P349-2111 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P349-2111 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P349-2111?
Check Price and Availability of P349-2111, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P349-2111 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P349-2111
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P349-2111
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P349-2111 available by request