P349-2393 Screening compound: 1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}propan-1-one

P349-2393 Screening compound: 1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}propan-1-one
P349-2393 Screening compound: 1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P349-2393
1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P349-2393

Molecular Formula

C23H27N5O4 (C23 H27 N5 O4)

Compound Name

1-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[1,2-a]pyrazin-3-yl]amino}propan-1-one

IUPAC name

1-{14-dioxa-8-azaspiro[4.5]decan-8-yl}-3-{[2-(3-methoxyphenyl)imidazo[12-a]pyrazin-3-yl]amino}propan-1-one

SMILES

COc1cccc(-c2c(NCCC(N(CC3)CCC33OCCO3)=O)n(ccnc3)c3n2)c1

InChI

InChI=1S/C23H27N5O4/c1-30-18-4-2-3-17(15-18)21-22(28-12-9-24-16-19(28)26-21)25-8-5-20(29)27-10-6-23(7-11-27)31-13-14-32-23/h2-4,9,12,15-16,25H,5-8,10-11,13-14H2,1H3

InChI Key

KNHCNXIFSSIUBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573580

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.400

Distribution Coefficient, logD

1.398

Water Solubility, LogSw

-1.59

Polar Surface Area

66.733

Acid Dissociation Constant (pKa)

20.73

Base Dissociation Constant (pKb)

4.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

P349-2393 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P349-2393 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P349-2393?
Check Price and Availability of P349-2393, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P349-2393 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P349-2393
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P349-2393
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P349-2393 available by request