P364-1711 Screening compound: 4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-2-carboxamide

P364-1711 Screening compound: 4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-2-carboxamide
P364-1711 Screening compound: 4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P364-1711
4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P364-1711

Molecular Formula

C19H12F3N5O2S (C19 H12 F3 N5 O2 S)

Compound Name

4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-2-carboxamide

IUPAC name

4-[3-(pyridin-4-yl)-124-oxadiazol-5-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}-13-thiazole-2-carboxamide

SMILES

O=C(c1nc(-c2nc(-c3ccncc3)no2)cs1)NCc1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C19H12F3N5O2S/c20-19(21,22)13-3-1-2-11(8-13)9-24-16(28)18-25-14(10-30-18)17-26-15(27-29-17)12-4-6-23-7-5-12/h1-8,10H,9H2,(H,24,28)

InChI Key

OQYIKTLQIZISMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27573781

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.957

Distribution Coefficient, logD

3.957

Water Solubility, LogSw

-4.13

Polar Surface Area

75.491

Acid Dissociation Constant (pKa)

12.84

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

P364-1711 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with P364-1711 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P364-1711?
Check Price and Availability of P364-1711, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P364-1711 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P364-1711
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P364-1711
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P364-1711 available by request