P368-0175 Screening compound: 1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinolin-2-yl}ethan-1-one

P368-0175 Screening compound: 1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinolin-2-yl}ethan-1-one
P368-0175 Screening compound: 1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinolin-2-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P368-0175
1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinolin-2-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P368-0175

Molecular Formula

C23H27N3O2 (C23 H27 N3 O2)

Compound Name

1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1,2,3,4-tetrahydroisoquinolin-2-yl}ethan-1-one

IUPAC name

1-{1-[4-(4-methylphenyl)piperazine-1-carbonyl]-1234-tetrahydroisoquinolin-2-yl}ethan-1-one

SMILES

CC(N(CC1)C(C(N(CC2)CCN2c2ccc(C)cc2)=O)c2c1cccc2)=O

InChI

InChI=1S/C23H27N3O2/c1-17-7-9-20(10-8-17)24-13-15-25(16-14-24)23(28)22-21-6-4-3-5-19(21)11-12-26(22)18(2)27/h3-10,22H,11-16H2,1-2H3/t22-/m1/s1

InChI Key

PDDVVXHYQFIHRC-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD27573859

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.242

Distribution Coefficient, logD

3.242

Water Solubility, LogSw

-3.13

Polar Surface Area

36.781

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

P368-0175 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P368-0175 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P368-0175?
Check Price and Availability of P368-0175, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P368-0175 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P368-0175
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P368-0175
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P368-0175 available by request