P387-1120 Screening compound: N~1~-{2-[(1-methyl-4-piperidyl)oxy]-3-pyridyl}-4-phenylbutanamide

P387-1120 Screening compound: N~1~-{2-[(1-methyl-4-piperidyl)oxy]-3-pyridyl}-4-phenylbutanamide
P387-1120 Screening compound: N~1~-{2-[(1-methyl-4-piperidyl)oxy]-3-pyridyl}-4-phenylbutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P387-1120
N~1~-{2-[(1-methyl-4-piperidyl)oxy]-3-pyridyl}-4-phenylbutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P387-1120

Molecular Formula

C21H27N3O2 (C21 H27 N3 O2)

Compound Name

N~1~-{2-[(1-methyl-4-piperidyl)oxy]-3-pyridyl}-4-phenylbutanamide

IUPAC name

n/a

SMILES

CN(CC1)CCC1Oc(nccc1)c1NC(CCCc1ccccc1)=O

InChI

InChI=1S/C21H27N3O2/c1-24-15-12-18(13-16-24)26-21-19(10-6-14-22-21)23-20(25)11-5-9-17-7-3-2-4-8-17/h2-4,6-8,10,14,18H,5,9,11-13,15-16H2,1H3,(H,23,25)

InChI Key

MPPOIPXOXCFQEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28993991

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.861

Distribution Coefficient, logD

0.741

Water Solubility, LogSw

-3.33

Polar Surface Area

42.154

Acid Dissociation Constant (pKa)

9.76

Base Dissociation Constant (pKb)

9.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

P387-1120 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with P387-1120 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P387-1120?
Check Price and Availability of P387-1120, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P387-1120 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P387-1120
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P387-1120
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P387-1120 available by request