P389-1112 Screening compound: 4-{[5-(methylamino)-2-pyridyl]oxy}-N~1~-propyltetrahydro-1(2H)-pyridinecarboxamide

P389-1112 Screening compound: 4-{[5-(methylamino)-2-pyridyl]oxy}-N~1~-propyltetrahydro-1(2H)-pyridinecarboxamide
P389-1112 Screening compound: 4-{[5-(methylamino)-2-pyridyl]oxy}-N~1~-propyltetrahydro-1(2H)-pyridinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P389-1112
4-{[5-(methylamino)-2-pyridyl]oxy}-N~1~-propyltetrahydro-1(2H)-pyridinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P389-1112

Molecular Formula

C15H24N4O2 (C15 H24 N4 O2)

Compound Name

4-{[5-(methylamino)-2-pyridyl]oxy}-N~1~-propyltetrahydro-1(2H)-pyridinecarboxamide

IUPAC name

4-{[5-(methylamino)pyridin-2-yl]oxy}-N-propylpiperidine-1-carboxamide

SMILES

CCCNC(N(CC1)CCC1Oc(cc1)ncc1NC)=O

InChI

InChI=1S/C15H24N4O2/c1-3-8-17-15(20)19-9-6-13(7-10-19)21-14-5-4-12(16-2)11-18-14/h4-5,11,13,16H,3,6-10H2,1-2H3,(H,17,20)

InChI Key

FDMZLJUXQGOOJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996233

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

292.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.016

Distribution Coefficient, logD

2.015

Water Solubility, LogSw

-2.41

Polar Surface Area

53.099

Acid Dissociation Constant (pKa)

17.02

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

P389-1112 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P389-1112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P389-1112?
Check Price and Availability of P389-1112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P389-1112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P389-1112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P389-1112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P389-1112 available by request