P391-0946 Screening compound: N,N-dimethyl-2-[(1-methyl-4-piperidyl)oxy]nicotinamide

P391-0946 Screening compound: N,N-dimethyl-2-[(1-methyl-4-piperidyl)oxy]nicotinamide
P391-0946 Screening compound: N,N-dimethyl-2-[(1-methyl-4-piperidyl)oxy]nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P391-0946
N,N-dimethyl-2-[(1-methyl-4-piperidyl)oxy]nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P391-0946

Molecular Formula

C14H21N3O2 (C14 H21 N3 O2)

Compound Name

N,N-dimethyl-2-[(1-methyl-4-piperidyl)oxy]nicotinamide

IUPAC name

NN-dimethyl-2-[(1-methylpiperidin-4-yl)oxy]pyridine-3-carboxamide

SMILES

CN(C)C(c(cccn1)c1OC1CCN(C)CC1)=O

InChI

InChI=1S/C14H21N3O2/c1-16(2)14(18)12-5-4-8-15-13(12)19-11-6-9-17(3)10-7-11/h4-5,8,11H,6-7,9-10H2,1-3H3

InChI Key

BEVVRCUFBCZYDS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30462126

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

263.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

0.031

Distribution Coefficient, logD

-2.089

Water Solubility, LogSw

-1.75

Polar Surface Area

35.975

Acid Dissociation Constant (pKa)

25.89

Base Dissociation Constant (pKb)

9.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.14

P391-0946 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • Epigenetic

References: we are preparing a list of scientific research reports with P391-0946 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P391-0946?
Check Price and Availability of P391-0946, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P391-0946 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P391-0946
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P391-0946
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P391-0946 available by request