P391-0972 Screening compound: 2-[(1-methyl-4-piperidyl)oxy]-N~3~-(2-pyridyl)nicotinamide

P391-0972 Screening compound: 2-[(1-methyl-4-piperidyl)oxy]-N~3~-(2-pyridyl)nicotinamide
P391-0972 Screening compound: 2-[(1-methyl-4-piperidyl)oxy]-N~3~-(2-pyridyl)nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P391-0972
2-[(1-methyl-4-piperidyl)oxy]-N~3~-(2-pyridyl)nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P391-0972

Molecular Formula

C17H20N4O2 (C17 H20 N4 O2)

Compound Name

2-[(1-methyl-4-piperidyl)oxy]-N~3~-(2-pyridyl)nicotinamide

IUPAC name

2-[(1-methylpiperidin-4-yl)oxy]-N-(pyridin-2-yl)pyridine-3-carboxamide

SMILES

CN(CC1)CCC1Oc(nccc1)c1C(Nc1ncccc1)=O

InChI

InChI=1S/C17H20N4O2/c1-21-11-7-13(8-12-21)23-17-14(5-4-10-19-17)16(22)20-15-6-2-3-9-18-15/h2-6,9-10,13H,7-8,11-12H2,1H3,(H,18,20,22)

InChI Key

BREDLBKBSIPRFE-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

312.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.755

Distribution Coefficient, logD

-0.365

Water Solubility, LogSw

-2.40

Polar Surface Area

52.680

Acid Dissociation Constant (pKa)

7.68

Base Dissociation Constant (pKb)

9.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.29

P391-0972 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
  • Epigenetic

References: we are preparing a list of scientific research reports with P391-0972 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P391-0972?
Check Price and Availability of P391-0972, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P391-0972 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P391-0972
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P391-0972
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P391-0972 available by request