P391-0981 Screening compound: 2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide

P391-0981 Screening compound: 2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide
P391-0981 Screening compound: 2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P391-0981
2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P391-0981

Molecular Formula

C18H22N4O2 (C18 H22 N4 O2)

Compound Name

2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide

IUPAC name

2-(piperidin-4-yloxy)-N-[2-(pyridin-2-yl)ethyl]pyridine-3-carboxamide

SMILES

O=C(c(cccn1)c1OC1CCNCC1)NCCc1ncccc1

InChI

InChI=1S/C18H22N4O2/c23-17(21-13-6-14-4-1-2-9-20-14)16-5-3-10-22-18(16)24-15-7-11-19-12-8-15/h1-5,9-10,15,19H,6-8,11-13H2,(H,21,23)

InChI Key

ARUOGXKOTDJASI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996257

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

326.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.417

Distribution Coefficient, logD

-2.573

Water Solubility, LogSw

-1.92

Polar Surface Area

62.256

Acid Dissociation Constant (pKa)

11.58

Base Dissociation Constant (pKb)

10.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

P391-0981 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

New Agro Library (44492 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P391-0981 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P391-0981?
Check Price and Availability of P391-0981, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P391-0981 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P391-0981
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P391-0981
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P391-0981 available by request