P392-0396 Screening compound: 2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

P392-0396 Screening compound: 2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one
P392-0396 Screening compound: 2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P392-0396
2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P392-0396

Molecular Formula

C24H29N3O3 (C24 H29 N3 O3)

Compound Name

2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-(4-methylphenyl)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

SMILES

Cc1ccc(CC(N(CC2)CC2Oc(nccc2)c2C(N2CCCCC2)=O)=O)cc1

InChI

InChI=1S/C24H29N3O3/c1-18-7-9-19(10-8-18)16-22(28)27-15-11-20(17-27)30-23-21(6-5-12-25-23)24(29)26-13-3-2-4-14-26/h5-10,12,20H,2-4,11,13-17H2,1H3/t20-/m0/s1

InChI Key

OKURBTDXQNGDDG-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD28994573

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.108

Distribution Coefficient, logD

3.108

Water Solubility, LogSw

-3.20

Polar Surface Area

49.374

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

-0.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.80

P392-0396 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P392-0396 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P392-0396?
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What is the minimum amount of P392-0396 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P392-0396
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P392-0396
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P392-0396 available by request