P392-2072 Screening compound: N~3~,N~3~-dimethyl-2-({1-[(phenethylamino)carbonyl]tetrahydro-1H-pyrrol-3-yl}oxy)nicotinamide

P392-2072 Screening compound: N~3~,N~3~-dimethyl-2-({1-[(phenethylamino)carbonyl]tetrahydro-1H-pyrrol-3-yl}oxy)nicotinamide
P392-2072 Screening compound: N~3~,N~3~-dimethyl-2-({1-[(phenethylamino)carbonyl]tetrahydro-1H-pyrrol-3-yl}oxy)nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P392-2072
N~3~,N~3~-dimethyl-2-({1-[(phenethylamino)carbonyl]tetrahydro-1H-pyrrol-3-yl}oxy)nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P392-2072

Molecular Formula

C21H26N4O3 (C21 H26 N4 O3)

Compound Name

N~3~,N~3~-dimethyl-2-({1-[(phenethylamino)carbonyl]tetrahydro-1H-pyrrol-3-yl}oxy)nicotinamide

IUPAC name

NN-dimethyl-2-({1-[(2-phenylethyl)carbamoyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide

SMILES

CN(C)C(c1cccnc1OC(CC1)CN1C(NCCc1ccccc1)=O)=O

InChI

InChI=1S/C21H26N4O3/c1-24(2)20(26)18-9-6-12-22-19(18)28-17-11-14-25(15-17)21(27)23-13-10-16-7-4-3-5-8-16/h3-9,12,17H,10-11,13-15H2,1-2H3,(H,23,27)/t17-/m1/s1

InChI Key

PXMLHFMAZVVWDD-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD28999193

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.388

Distribution Coefficient, logD

1.388

Water Solubility, LogSw

-1.96

Polar Surface Area

59.238

Acid Dissociation Constant (pKa)

15.89

Base Dissociation Constant (pKb)

0.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

P392-2072 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P392-2072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P392-2072?
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What is the minimum amount of P392-2072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P392-2072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P392-2072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P392-2072 available by request