P392-3344 Screening compound: N-(3,4-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide

P392-3344 Screening compound: N-(3,4-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide
P392-3344 Screening compound: N-(3,4-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P392-3344
N-(3,4-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P392-3344

Molecular Formula

C23H28N4O4 (C23 H28 N4 O4)

Compound Name

N-(3,4-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide

IUPAC name

N-(34-dimethylphenyl)-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide

SMILES

Cc(cc1)c(C)cc1NC(N(CC1)CC1Oc1ncccc1C(N1CCOCC1)=O)=O

InChI

InChI=1S/C23H28N4O4/c1-16-5-6-18(14-17(16)2)25-23(29)27-9-7-19(15-27)31-21-20(4-3-8-24-21)22(28)26-10-12-30-13-11-26/h3-6,8,14,19H,7,9-13,15H2,1-2H3,(H,25,29)/t19-/m1/s1

InChI Key

XPVLPNZBTXLOPB-LJQANCHMSA-N

MDL Number (MFCD)

MFCD28999283

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.600

Distribution Coefficient, logD

2.600

Water Solubility, LogSw

-3.06

Polar Surface Area

66.631

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

0.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

P392-3344 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Targets:
  • Ion Channels
  • Kinases
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P392-3344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P392-3344?
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What is the minimum amount of P392-3344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P392-3344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P392-3344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P392-3344 available by request