P392-3377 Screening compound: N~1~-(2-furylmethyl)-3-{[3-(morpholinocarbonyl)-2-pyridyl]oxy}-1-pyrrolidinecarboxamide

P392-3377 Screening compound: N~1~-(2-furylmethyl)-3-{[3-(morpholinocarbonyl)-2-pyridyl]oxy}-1-pyrrolidinecarboxamide
P392-3377 Screening compound: N~1~-(2-furylmethyl)-3-{[3-(morpholinocarbonyl)-2-pyridyl]oxy}-1-pyrrolidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P392-3377
N~1~-(2-furylmethyl)-3-{[3-(morpholinocarbonyl)-2-pyridyl]oxy}-1-pyrrolidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P392-3377

Molecular Formula

C20H24N4O5 (C20 H24 N4 O5)

Compound Name

N~1~-(2-furylmethyl)-3-{[3-(morpholinocarbonyl)-2-pyridyl]oxy}-1-pyrrolidinecarboxamide

IUPAC name

N-[(furan-2-yl)methyl]-3-{[3-(morpholine-4-carbonyl)pyridin-2-yl]oxy}pyrrolidine-1-carboxamide

SMILES

O=C(c1cccnc1OC(CC1)CN1C(NCc1ccco1)=O)N1CCOCC1

InChI

InChI=1S/C20H24N4O5/c25-19(23-8-11-27-12-9-23)17-4-1-6-21-18(17)29-16-5-7-24(14-16)20(26)22-13-15-3-2-10-28-15/h1-4,6,10,16H,5,7-9,11-14H2,(H,22,26)/t16-/m1/s1

InChI Key

KYWHZEDKEIMIGC-MRXNPFEDSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.991

Distribution Coefficient, logD

0.991

Water Solubility, LogSw

-1.89

Polar Surface Area

75.702

Acid Dissociation Constant (pKa)

14.33

Base Dissociation Constant (pKb)

-0.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.00

P392-3377 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P392-3377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P392-3377?
Check Price and Availability of P392-3377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P392-3377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P392-3377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P392-3377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P392-3377 available by request