P393-0625 Screening compound: 4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine

P393-0625 Screening compound: 4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine
P393-0625 Screening compound: 4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound P393-0625
4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P393-0625

Molecular Formula

C20H23N3O4S (C20 H23 N3 O4 S)

Compound Name

4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine

IUPAC name

4-(6-{[1-(thiophene-3-carbonyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine

SMILES

O=C(c1cscc1)N(CC1)CCC1Oc(cc1)ncc1C(N1CCOCC1)=O

InChI

InChI=1S/C20H23N3O4S/c24-19(23-8-10-26-11-9-23)15-1-2-18(21-13-15)27-17-3-6-22(7-4-17)20(25)16-5-12-28-14-16/h1-2,5,12-14,17H,3-4,6-11H2

InChI Key

UHYPRPQOWGAUOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28994644

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.247

Distribution Coefficient, logD

1.247

Water Solubility, LogSw

-1.89

Polar Surface Area

57.761

Acid Dissociation Constant (pKa)

25.58

Base Dissociation Constant (pKb)

0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

P393-0625 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GABA Library (7115 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Eye
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • GPCR
  • Ion Channels
  • GPCR
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P393-0625 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P393-0625?
Check Price and Availability of P393-0625, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P393-0625 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P393-0625
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P393-0625
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P393-0625 available by request