P393-0691 Screening compound: (6-{[1-(3-methylbenzoyl)-4-piperidyl]oxy}-3-pyridyl)(morpholino)methanone

P393-0691 Screening compound: (6-{[1-(3-methylbenzoyl)-4-piperidyl]oxy}-3-pyridyl)(morpholino)methanone
P393-0691 Screening compound: (6-{[1-(3-methylbenzoyl)-4-piperidyl]oxy}-3-pyridyl)(morpholino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P393-0691
(6-{[1-(3-methylbenzoyl)-4-piperidyl]oxy}-3-pyridyl)(morpholino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P393-0691

Molecular Formula

C23H27N3O4 (C23 H27 N3 O4)

Compound Name

(6-{[1-(3-methylbenzoyl)-4-piperidyl]oxy}-3-pyridyl)(morpholino)methanone

IUPAC name

4-(6-{[1-(3-methylbenzoyl)piperidin-4-yl]oxy}pyridine-3-carbonyl)morpholine

SMILES

Cc1cccc(C(N(CC2)CCC2Oc(cc2)ncc2C(N2CCOCC2)=O)=O)c1

InChI

InChI=1S/C23H27N3O4/c1-17-3-2-4-18(15-17)22(27)25-9-7-20(8-10-25)30-21-6-5-19(16-24-21)23(28)26-11-13-29-14-12-26/h2-6,15-16,20H,7-14H2,1H3

InChI Key

PQFMXBJLWWUHHU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30460209

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.719

Distribution Coefficient, logD

1.719

Water Solubility, LogSw

-1.86

Polar Surface Area

56.743

Acid Dissociation Constant (pKa)

25.58

Base Dissociation Constant (pKb)

0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.48

P393-0691 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P393-0691 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P393-0691?
Check Price and Availability of P393-0691, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P393-0691 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P393-0691
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P393-0691
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P393-0691 available by request