P393-0952 Screening compound: N,N-dimethyl-6-[(1-phenethyl-4-piperidyl)oxy]nicotinamide

P393-0952 Screening compound: N,N-dimethyl-6-[(1-phenethyl-4-piperidyl)oxy]nicotinamide
P393-0952 Screening compound: N,N-dimethyl-6-[(1-phenethyl-4-piperidyl)oxy]nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P393-0952
N,N-dimethyl-6-[(1-phenethyl-4-piperidyl)oxy]nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P393-0952

Molecular Formula

C21H27N3O2 (C21 H27 N3 O2)

Compound Name

N,N-dimethyl-6-[(1-phenethyl-4-piperidyl)oxy]nicotinamide

IUPAC name

NN-dimethyl-6-{[1-(2-phenylethyl)piperidin-4-yl]oxy}pyridine-3-carboxamide

SMILES

CN(C)C(c(cc1)cnc1OC1CCN(CCc2ccccc2)CC1)=O

InChI

InChI=1S/C21H27N3O2/c1-23(2)21(25)18-8-9-20(22-16-18)26-19-11-14-24(15-12-19)13-10-17-6-4-3-5-7-17/h3-9,16,19H,10-15H2,1-2H3

InChI Key

GWRNNDJZKMUOSE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29018131

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.129

Distribution Coefficient, logD

0.684

Water Solubility, LogSw

-2.21

Polar Surface Area

35.250

Acid Dissociation Constant (pKa)

25.89

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

P393-0952 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P393-0952 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P393-0952?
Check Price and Availability of P393-0952, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P393-0952 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P393-0952
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P393-0952
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P393-0952 available by request