P393-0980 Screening compound: N~3~-(1-methyl-4-piperidyl)-6-[(1-methyl-4-piperidyl)oxy]nicotinamide

P393-0980 Screening compound: N~3~-(1-methyl-4-piperidyl)-6-[(1-methyl-4-piperidyl)oxy]nicotinamide
P393-0980 Screening compound: N~3~-(1-methyl-4-piperidyl)-6-[(1-methyl-4-piperidyl)oxy]nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P393-0980
N~3~-(1-methyl-4-piperidyl)-6-[(1-methyl-4-piperidyl)oxy]nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P393-0980

Molecular Formula

C18H28N4O2 (C18 H28 N4 O2)

Compound Name

N~3~-(1-methyl-4-piperidyl)-6-[(1-methyl-4-piperidyl)oxy]nicotinamide

IUPAC name

N-(1-methylpiperidin-4-yl)-6-[(1-methylpiperidin-4-yl)oxy]pyridine-3-carboxamide

SMILES

CN(CC1)CCC1NC(c(cc1)cnc1OC1CCN(C)CC1)=O

InChI

InChI=1S/C18H28N4O2/c1-21-9-5-15(6-10-21)20-18(23)14-3-4-17(19-13-14)24-16-7-11-22(2)12-8-16/h3-4,13,15-16H,5-12H2,1-2H3,(H,20,23)

InChI Key

NSUXEGOPANHPFA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28993912

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.504

Distribution Coefficient, logD

-1.914

Water Solubility, LogSw

-1.72

Polar Surface Area

46.822

Acid Dissociation Constant (pKa)

14.80

Base Dissociation Constant (pKb)

9.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.67

P393-0980 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Bromodomain Modulators Library (5801 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P393-0980 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P393-0980?
Check Price and Availability of P393-0980, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P393-0980 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P393-0980
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P393-0980
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P393-0980 available by request