P394-1084 Screening compound: 6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide

P394-1084 Screening compound: 6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide
P394-1084 Screening compound: 6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P394-1084
6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P394-1084

Molecular Formula

C16H18N4O2 (C16 H18 N4 O2)

Compound Name

6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide

IUPAC name

6-({1-[(pyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pyridine-3-carboxamide

SMILES

NC(c(cc1)cnc1OC1CN(Cc2ncccc2)CC1)=O

InChI

InChI=1S/C16H18N4O2/c17-16(21)12-4-5-15(19-9-12)22-14-6-8-20(11-14)10-13-3-1-2-7-18-13/h1-5,7,9,14H,6,8,10-11H2,(H2,17,21)/t14-/m0/s1

InChI Key

ADHIXLVPQRLKFC-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD28996241

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

298.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.403

Distribution Coefficient, logD

0.244

Water Solubility, LogSw

-1.20

Polar Surface Area

63.172

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

7.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.25

P394-1084 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Ion Channels
  • GPCR
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P394-1084 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P394-1084?
Check Price and Availability of P394-1084, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P394-1084 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P394-1084
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P394-1084
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P394-1084 available by request