P396-1518 Screening compound: [3-({3-[methyl(propyl)amino]-2-pyrazinyl}oxy)-1-pyrrolidinyl](1H-pyrazol-3-yl)methanone

P396-1518 Screening compound: [3-({3-[methyl(propyl)amino]-2-pyrazinyl}oxy)-1-pyrrolidinyl](1H-pyrazol-3-yl)methanone
P396-1518 Screening compound: [3-({3-[methyl(propyl)amino]-2-pyrazinyl}oxy)-1-pyrrolidinyl](1H-pyrazol-3-yl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P396-1518
[3-({3-[methyl(propyl)amino]-2-pyrazinyl}oxy)-1-pyrrolidinyl](1H-pyrazol-3-yl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P396-1518

Molecular Formula

C16H22N6O2 (C16 H22 N6 O2)

Compound Name

[3-({3-[methyl(propyl)amino]-2-pyrazinyl}oxy)-1-pyrrolidinyl](1H-pyrazol-3-yl)methanone

IUPAC name

n/a

SMILES

CCCN(C)c1nccnc1OC(CC1)CN1C(c1n[nH]cc1)=O

InChI

InChI=1S/C16H22N6O2/c1-3-9-21(2)14-15(18-8-7-17-14)24-12-5-10-22(11-12)16(23)13-4-6-19-20-13/h4,6-8,12H,3,5,9-11H2,1-2H3,(H,19,20)/t12-/m1/s1

InChI Key

CYYDDLQQCIGRED-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD28999418

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.379

Distribution Coefficient, logD

1.379

Water Solubility, LogSw

-1.95

Polar Surface Area

69.040

Acid Dissociation Constant (pKa)

10.20

Base Dissociation Constant (pKb)

6.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

P396-1518 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P396-1518 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P396-1518?
Check Price and Availability of P396-1518, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P396-1518 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P396-1518
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P396-1518
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P396-1518 available by request