P396-1535 Screening compound: 4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine

P396-1535 Screening compound: 4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine
P396-1535 Screening compound: 4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound P396-1535
4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P396-1535

Molecular Formula

C15H24N4O4S (C15 H24 N4 O4 S)

Compound Name

4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine

IUPAC name

4-(3-{[1-(propane-1-sulfonyl)pyrrolidin-3-yl]oxy}pyrazin-2-yl)morpholine

SMILES

CCCS(N(CC1)CC1Oc1nccnc1N1CCOCC1)(=O)=O

InChI

InChI=1S/C15H24N4O4S/c1-2-11-24(20,21)19-6-3-13(12-19)23-15-14(16-4-5-17-15)18-7-9-22-10-8-18/h4-5,13H,2-3,6-12H2,1H3/t13-/m1/s1

InChI Key

VQKNSLQKMLXMMZ-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD28999424

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.097

Distribution Coefficient, logD

1.097

Water Solubility, LogSw

-1.76

Polar Surface Area

68.823

Acid Dissociation Constant (pKa)

22.48

Base Dissociation Constant (pKb)

2.28

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

73.30

P396-1535 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P396-1535 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P396-1535?
Check Price and Availability of P396-1535, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P396-1535 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P396-1535
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P396-1535
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P396-1535 available by request