P396-1627 Screening compound: 1-(3-{[3-(2,3-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one

P396-1627 Screening compound: 1-(3-{[3-(2,3-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one
P396-1627 Screening compound: 1-(3-{[3-(2,3-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P396-1627
1-(3-{[3-(2,3-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P396-1627

Molecular Formula

C19H22N4O3 (C19 H22 N4 O3)

Compound Name

1-(3-{[3-(2,3-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one

IUPAC name

1-(3-{[3-(23-dihydro-1H-indol-1-yl)pyrazin-2-yl]oxy}pyrrolidin-1-yl)-2-methoxyethan-1-one

SMILES

COCC(N(CC1)CC1Oc1nccnc1N(CC1)c2c1cccc2)=O

InChI

InChI=1S/C19H22N4O3/c1-25-13-17(24)22-10-7-15(12-22)26-19-18(20-8-9-21-19)23-11-6-14-4-2-3-5-16(14)23/h2-5,8-9,15H,6-7,10-13H2,1H3

InChI Key

HGBFBJPFAMMELU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28999995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.772

Distribution Coefficient, logD

1.771

Water Solubility, LogSw

-1.85

Polar Surface Area

52.885

Acid Dissociation Constant (pKa)

22.40

Base Dissociation Constant (pKb)

4.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

P396-1627 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Aging Library (44940 compounds)

CNS MPO Library (28609 compounds)

Indole Derivatives (10091 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Cyclic compounds
Targets:
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with P396-1627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P396-1627?
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What is the minimum amount of P396-1627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P396-1627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P396-1627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P396-1627 available by request