P396-1636 Screening compound: 1-(3-{[1-(2-pyridylmethyl)tetrahydro-1H-pyrrol-3-yl]oxy}-2-pyrazinyl)indoline

P396-1636 Screening compound: 1-(3-{[1-(2-pyridylmethyl)tetrahydro-1H-pyrrol-3-yl]oxy}-2-pyrazinyl)indoline
P396-1636 Screening compound: 1-(3-{[1-(2-pyridylmethyl)tetrahydro-1H-pyrrol-3-yl]oxy}-2-pyrazinyl)indoline alternative view

Chemical Structure Depiction of ChemDiv screening compound P396-1636
1-(3-{[1-(2-pyridylmethyl)tetrahydro-1H-pyrrol-3-yl]oxy}-2-pyrazinyl)indoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P396-1636

Molecular Formula

C22H23N5O (C22 H23 N5 O)

Compound Name

1-(3-{[1-(2-pyridylmethyl)tetrahydro-1H-pyrrol-3-yl]oxy}-2-pyrazinyl)indoline

IUPAC name

n/a

SMILES

C(c1ncccc1)N(CC1)CC1Oc1nccnc1N(CC1)c2c1cccc2

InChI

InChI=1S/C22H23N5O/c1-2-7-20-17(5-1)8-14-27(20)21-22(25-12-11-24-21)28-19-9-13-26(16-19)15-18-6-3-4-10-23-18/h1-7,10-12,19H,8-9,13-16H2/t19-/m0/s1

InChI Key

CGUSQRJZRVEYAC-IBGZPJMESA-N

MDL Number (MFCD)

MFCD28999409

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.904

Distribution Coefficient, logD

2.672

Water Solubility, LogSw

-3.10

Polar Surface Area

41.344

Acid Dissociation Constant (pKa)

24.54

Base Dissociation Constant (pKb)

7.25

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

P396-1636 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Eye
  • Cancer
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P396-1636 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P396-1636?
Check Price and Availability of P396-1636, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P396-1636 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P396-1636
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P396-1636
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P396-1636 available by request